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OCTA Study of Choroidal Vasculature in Open Angle Glaucoma Patients

OCTA as a New Biomarker in the Pathogenesis of Primary Open Angle Glaucoma

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05455567
Enrollment
57
Registered
2022-07-13
Start date
2022-02-01
Completion date
2022-05-15
Last updated
2022-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma Open-Angle Primary

Brief summary

The aim of the present study was to examine and measure SFCT and CCVD using respectively EDI-OCT and OCTA in preperimetric and advanced glaucomatous eyes, in order to shed light on the vascular pathogenesis of glaucoma disease.

Interventions

DIAGNOSTIC_TESTOCTA

Choriocapillary vessel density calculated with OCTA

Sponsors

Federico II University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
40 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

• age older than 40 years * diagnosis of glaucoma * absence of diabetes, heart diseases, hypertension * absence of drug intake * absence of vitreoretinal, vascular retinal diseases * absence of previous ocular surgery and congenital eye diseases. * absence of errors of refraction * absence of lens opacities * absence of low-quality OCT and OCTA images

Exclusion criteria

* age younger than 40 years * presence of diabetes, heart diseases, hypertension * vitreoretinal and vascular retinal diseases * previous ocular surgery and congenital eye diseases * errors of refraction * lens opacities * low-quality OCT and OCTA images

Design outcomes

Primary

MeasureTime frameDescription
The measurements of choroidal thickness and choriocapillary vessel density in patients with open angle glaucoma.up to 5 monthscorrelation of measurement of choroidal thickness and choriocapillary vessel density in three different patients groups

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026