Preoperative Renal Insufficiency Predicts Postoperative Adverse Outcomes

Preoperative Renal Insufficiency Predicts Postoperative Adverse Outcomes: A Matched Cohort Study Using the NSQIP Database

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05455528

Enrollment

2421286

Registered

2022-07-13

Start date

2022-01-01

Completion date

2022-07-01

Last updated

2022-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Morality, Renal Insufficiency

Brief summary

The main purpose of this study is to evaluate the risk of postoperative mortality and complications in surgical populations with preoperative renal insufficiency.

Detailed description

This retrospective cohort study use the National Surgical Quality Improvement Program (NSQIP) database to evaluate the risk of postoperative morbidity and mortality in the surgical population. Patients with estimated. glomerular filtration rate(GFR) \< 60 ml/min per 1.73 square meter are defined as the renal insufficiency group. Patients with estimated GFR \> 90 ml/min per 1.73 square meter are defined as patients without renal insufficiency. Propensity score-matching methods and multivariate logistic regression are used to calculate the risk of postoperative morbidity and mortality.

Interventions

DIAGNOSTIC_TESTestimated GFR calculation

The estimated GFR is computed with Modification of Diet in Renal Disease (MDRD) formula

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients with estimated GFR \< 60 ml/min per 1.73 square meter or currently on dialysis are included in renal insufficiency group. * Patients with estimated GFR \> 90 ml/min per 1.73 square meter are included in non-renal insufficiency group

Exclusion criteria

* Patients population with estimated GFR between 60-90 is not included in the study

Design outcomes

Primary

Measure	Time frame	Description
Risk of postoperative mortality	30 days after surgery date	Calculate risk of postoperative 30-day in-hospital mortality between groups

Secondary

Measure	Time frame	Description
Risk of postoperative morbidities	30 days after surgery date	Postoperative events, including pneumonia, septic shock, stroke, deep vein thrombosis/thrombophlebitis, myocardial infarction and postoperative bleeding are included

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026