The South-East Asian Transgender Health Cohort

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05454579

Acronym

SEATrans

Enrollment

450

Registered

2022-07-12

Start date

2022-12-02

Completion date

2025-03-30

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HCV, HIV, STIs

Keywords

HIV

Brief summary

This is a prospective observational cohort study that will enroll 300 HIV-negative transgender people and 150 transgender people living with HIV from 4 community health centers in Thailand, Vietnam, and the Philippines. Each participant will be followed-up until the completion of 24 months.

Detailed description

This prospective observational cohort study will longitudinally track physical (e.g. HIV/STI, sexual risk behavior, gender affirmation, clinical information, cardiovascular health, medical history) and mental health (e.g. stigma and discrimination, gender-based violence, anxiety, depression); identify biomedical, structural, and psychosocial factors impacting physical and mental health among transgender people; describe the structural barriers to healthcare experienced by transgender people as well as develop the guidance on holistic healthcare policies for transgender people.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Thai/Vietnamese/Filipino nationality * Aged ≥ 18 years old * Self-identify as a transgender woman or transgender man * Have signed consent form

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame	Description
New cases of HIV infection in transgender people	24 months	Longitudinally evaluate medical conditions in physiology by using self-administered questionnaires (e.g. sexual behavioral risk assessment) and laboratory results of anti-HIV over 24 months of follow-up.
Mental health status in transgender people	24 months	Longitudinally evaluate the mental health as well as gender violence, stigma, discrimination, substance use, etc. by using self-administered questionnaires (e.g. mental health assessment, psychosocial assessment) including gender affirmation in primary care (e.g., hormones and/or surgical interventions history).
Structural factors and psychosocial factors that impact the physiology and mental health of transgender people	24 months	This is related to no.2 and will be collected by using the same questionnaires of self-administered. After collecting and grouping the data, we will know the structure and psychosocial problems that impact the health care system's access of transgender people.

Countries

Philippines, Thailand, Vietnam

Contacts

PRINCIPAL_INVESTIGATORNittaya Phanuphak, MD,PhD.

Institute of HIV Research and Innovation

Outcome results