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A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients

A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05454397
Enrollment
2000
Registered
2022-07-12
Start date
2022-09-01
Completion date
2023-10-15
Last updated
2022-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Stroke

Keywords

Stroke; Dysphagia;Nutrition management;

Brief summary

Stroke is the leading cause of premature death and disability, and early recognition and treatment of dysphagia is fundamental to stroke management. Early and full tube feeding in the acute phase of stroke helps to address nutritional problems resulting from dysphagia and impaired consciousness and helps to reduce morbidity and mortality and poor outcomes. Current guidelines for acute stroke management do not address the goal of tube feeding of enteral nutrition for energy and protein. In the treatment of acute stroke, there is a strong global focus on pharmacological thrombolysis or mechanical thrombolysis, with nutritional interventions being a less explored topic. Real-world evidence on large samples, feeding attainment and outcomes, and nutrition in the acute phase of stroke is lacking in China . The aim of this study was to understand the current status of nutritional therapy in stroke hospitalization in neurology and its impact on prognosis nationwide, and to improve the standardized management process of enteral nutrition therapy in the acute phase of stroke.

Detailed description

Malnutrition is a common geriatric syndrome with a disproportionate incidence in geriatric and neurology inpatients. In recent years, national nutritional surveys of geriatric inpatients have shown that about 2/3 of geriatric inpatients have nutritional problems; only half of neurology inpatients at high risk receive nutritional support, and inadequate nutrition exacerbates primary disease, increases complications, makes hospital stays longer, and ultimately affects patient survival outcomes. To increase comprehensive and up-to-date research on the current status of nutritional therapy in geriatric and neurology inpatients, and to lay the foundation for future standardized treatment and standardized management, we conducted a nationwide survey on the current status of nutritional risk screening and treatment in geriatric and neurology inpatients. The aim is to raise the level of clinicians' awareness of malnutrition and nutritional risk in hospitalized patients, standardize clinical practice, and properly implement nutritional support to improve patients' clinical outcomes.

Interventions

Observational study, no intervention

Sponsors

First Affiliated Hospital of Fujian Medical University
CollaboratorOTHER
Yantai Yuhuangding Hospital
CollaboratorOTHER
The First Hospital of Jilin University
CollaboratorOTHER
Qilu Hospital of Shandong University
CollaboratorOTHER
ZHEJIANG PROVINCE XIAOSHAN HOSPITAL
CollaboratorUNKNOWN
Affiliated Wenling Hospital of Wenzhou Medical University
CollaboratorOTHER
Ganzhou People's Hospital
CollaboratorUNKNOWN
Affiliated Hospital of Jining Medical hospital
CollaboratorUNKNOWN
Henan Provincial People's Hospital
CollaboratorOTHER
Zhongda Hospital
CollaboratorOTHER
The Second Affiliated Hospital of Harbin Medical University
CollaboratorOTHER
The First People's Hospital of Kunshan
CollaboratorOTHER
The 2nd Affiliated Hospital of Wenzhou Medical University
CollaboratorUNKNOWN
THE FIRST PEOPLE'S HOSPITAL OF JIASHAN
CollaboratorUNKNOWN
First Affiliated Hospital Xi'an Jiaotong University
CollaboratorOTHER
Fujian Province Zhangzhou Hospital
CollaboratorUNKNOWN
People's Hospital of Chongqing
CollaboratorOTHER
Nanjing Zijin Hospital
CollaboratorUNKNOWN
Red Cross Hospital, Hangzhou, China
CollaboratorOTHER
Wenzhou Hospital of Chinese Medicine
CollaboratorUNKNOWN
Kaifeng Central Hospital
CollaboratorOTHER
First Affiliated Hospital of Guangxi Medical University
CollaboratorOTHER
Zhongshan Hospital of Xiamen University
CollaboratorUNKNOWN
Xi'an Encephalopathy of Traditional Chinese Medicine Hospital
CollaboratorUNKNOWN
903 Hospital of Chinese People's Liberation Army
CollaboratorOTHER
Xiangya Hospital of Central South University
CollaboratorOTHER
Second Affiliated Hospital of Suzhou University
CollaboratorOTHER
Tongji Hospital
CollaboratorOTHER
The Affiliated Hospital o fQingdao University
CollaboratorUNKNOWN
The First Affiliated Hospital of Anhui Medical University
CollaboratorOTHER
Yancheng Third People's Hospital
CollaboratorUNKNOWN
Linyi People's Hospital
CollaboratorOTHER
Dongfang Hospital Beijing University of Chinese Medicine
CollaboratorOTHER
The Affiliated Hospital of Qingdao University
CollaboratorOTHER
Nanfang Hospital, Southern Medical University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Newly admitted stroke patients admitted to neurology, age ≥18 years, within 7 days of onset, expected survival \>3 months (i.e., not end-stage), expected neurology stay 7-10 days; * At risk of malnutrition (MUST ≥ 2 points) or at nutritional risk (NRS2002 ≥ 3 points), sign an informed notice.

Exclusion criteria

* Transferred during treatment, contraindications to nutritional therapy (e.g., hemodynamic instability, gastrointestinal bleeding (bleeding \>100 ml), other nutritional studies, pregnancy.

Design outcomes

Primary

MeasureTime frameDescription
Nutrition implementation rateThe first day of admission; the seventh day of admission; the day before discharge.Proportion of patients hospitalized for stroke who were given nutritional support
Nutrition compliance rate of stroke inpatientsThe first day of admission; the seventh day of admission; the day before discharge.Percentage of patients hospitalized for stroke whose nutritional indicators and nutritional status met the guidelines after being given nutritional support

Secondary

MeasureTime frameDescription
30-day post-discharge mortality30-day post-dischargeProportion of enrolled patients who died 30 days after discharge from the hospital
Infection rate30-day post-dischargeProportion of enrolled patients with pulmonary infection 30 days after discharge from hospital.
Readmission rate30-day post-dischargeProportion of patients enrolled who were readmitted for various reasons 30 days after discharge.
Functional prognosis30-day post-dischargeFunctional prognosis of the enrolled patients, such as life skills, motor and sensory functions, cognitive functions and swallowing functions.

Countries

China

Contacts

Primary ContactJinYu Chen, M.D.
568344684@qq.com+8615876578154

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026