Collagen Membrane, Free Gingival Graft, Socket Sealing
Conditions
Keywords
Alveolar sealing, Free gingival graft, Autogenous graft, Collagen matrix
Brief summary
The goal of this study was to compare, clinical and histologically, the use of the suine collagen matrix (Mucograft Seal \[MS\], Geisthlich®) and the free gingival graft (FGG) for the alveolar sealing after inserted bone graft biomaterial. It was included 18 patients with tooth referred to extraction (maxilar incisives, canines, or pre-molars) which were randomly divided in 2 groups, according to the material for alveolus sealing: control (FGG) and test (MS). After the minimally traumatic extraction, all the alveoli were filled with bovine mineral matrix (Bio-Oss®), and the material for alveolar sealing were positioned and stabilized with sutures. The follow-up (clinical and photographic) happened on the immediate post-operatory period, and with 3, 7, 15, 30, 60, 90, and 120 days. After 120 days, before implant placement, tissues samples were obtained with a 3.5mm punch scalpel for histological analysis. Qualitative information related to the patient's perception considering the treatment were collected.
Interventions
PROCEDURESocket preservation
Tooth extraction and preservation with a biomaterial
Sponsors
Universidade Salgado de Oliveira
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* patients ASA I * patients requiring single tooth extraction in the site between #4 to #13 * patients without enough bone volume for immediate implant placement.
Exclusion criteria
* patients with general contraindications for implant surgery * pregnant or lactating women * patients with untreated periodontitis * bruxism or severe clenching * immunosuppressed * patients with a previous history of irradiation of the head and neck area * uncontrolled diabetes * heavy smoker (\>10 cigarettes/day) * poor oral hygiene and low motivation * use of bisphosphonates * substance abuse such as alcohol or drugs and psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Radiographic and clinical analysis | 6 months | Socket preservation with xenograft biomaterial and another one to seal it (FGG or collagen membrane). Radiographic analysis - PA (periapical x-rays) comparing groups and periods of the follow-up. It was performed descriptive comparative analysis. Clinical evaluation - bleeding on probing (dichotomic analysis), ISQ (torque achieved - Osstell), qualitative analysis (questionnaire with 8 questions), and subjective appraisal of the soft tissue healing (according to the period of evaluation). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Histological analysis - Gingiva | 6 months | Gingival thickness obtained from the local tissue was evaluated through histological analysis (optical binocular microscope); assessment of the epithelial and connective layers (micrometers). |
Countries
United States
Outcome results
None listed