Corneal Endothelial Cell Loss, Pseudoexfoliation Syndrome
Conditions
Keywords
corneal endothelial cell loss, pseudoexfoliation syndrome , cataract
Brief summary
To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.
Detailed description
In a prospective interventional case-control study, 20 eyes with cataract and PEX and 20 control eyes with cataract without PXE were subjected to phacoemulsification and posterior chamber foldable intraocular lens implantation in Minia University Hospital and Genaidy Eye Center between March 2019 and December 2020. Specular microscopy was done preoperatively, 3 and 6 months postoperatively. Endothelium cell density (ECD), coefficient variation (CV), hexagonality, pleomorphism and corneal thickness were evaluated and compares between PXE and control eyes.
Interventions
PROCEDUREphacoemulsification
phacoemulsification with corneal endothelial evaluation by specular microscopy
Sponsors
Minia University
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* senile cataract age more than 55 years
Exclusion criteria
* PEX with glaucoma, eyes with cornea guttata or any corneal dystrophy, zonular dehiscence, very dense nuclear cataract (cataracta nigra) history of previous ocular surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| corneal endothelial cell loss | 6 months | corneal endothelial cell loss |
Countries
Egypt
Outcome results
None listed