Erectile Dysfunction, Erectile Dysfunction With Diabetes Mellitus
Conditions
Brief summary
The aim of this current study is to estimate serum level of YKL-40, serum total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3 months.
Interventions
DRUGTadalafil 5mg
* Estimate serum level of serum YKL-40, total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3months. * Penile color Doppler ultrasound examination before and after treatment
Sponsors
Aswan University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
30 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Diabetic patients with ED.
Exclusion criteria
* Patients with history of pelvic trauma. * Patients with major pelvic surgical intervention. * Patients with hypogonadism and hyperprolactinemia. * Patients with chronic liver disease. * Patients with cardio vascular system diseases. * History of chronic intake of central nervous system, anti androgen drugs or other drugs as Tramadol. * Smokers patients. * Patients with non-vasculogenic Erectile dysfunction.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum YKL-40 and platelets indices in erectile dysfunction | 3 months | Measurement of YKL-40 and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Effect of tadalafil on Erectile dysfucntion patients | 3 months | To show the therapeutic effect of tadalafil in dose 5 mg daily on Erectile dysfucntion patients and assess their response by international index of erectile function (IIEF-5) |
Countries
Egypt
Outcome results
None listed