Atrial Fibrillation New Onset
Conditions
Brief summary
Screening for Atrial Fibrillation in Elderly Women (SAFE-W) is a pilot study evaluating the prevalence of atrial fibrillation (Afib) in a rapidly aging segment of the population. Studies have shown that women with Afib are more likely to be symptomatic, have increased mortality from stroke resulting from Afib, and are less likely to receive treatment for Afib. University of Maryland Department of Neurology and Vascular Neurology are recruiting women older than 70 years of age to participate in the study.
Detailed description
Atrial fibrillation or irregular heart beat is seen in 1/3rd of patients that present with stroke. Atrial fibrillation is being increasingly seen in women older than 70 as women are likely to live longer. Women are more likely to die from atrial fibrillation related stroke and are more likely to have symptoms from uncontrolled atrial fibrillation. They are also less likely to be treated with blood thinners to prevent stroke. This section of the population has been underrepresented in other studies on atrial fibrillation and the aim of this study is to proactively screen women older than 70 who are at risk for atrial fibrillation by using a wearable cardiac monitor.
Interventions
DEVICEWearable cardiac monitor -Zio patch
Women older than 70 years old will be asked to wear a cutaneous cardiac monitor for 2 weeks.
Sponsors
University of Maryland, Baltimore
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
70 Years to 100 Years
Healthy volunteers
Yes
Inclusion criteria
1. Female sex 2. No previous diagnosis of atrial fibrillation 3. Age ≥70 years 4. CHA2DS2-VASc score ≥4
Exclusion criteria
1. Life expectancy \< 2 years 2. Dementia or other neurologic condition which would make outpatient follow-up difficult 3. CHA2DS2-VASc score ≤3 4. Any compliance issues - such as heavy alcohol/drug use that would impede follow up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of detection of atrial fibrillation | 1 year | Percentage of women older than 70 found to have atrial fibrillation one year from enrollment |
| Anticoagulant use for prevention of stroke | 2 years | Rate of anticoagulant prescription |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Device adherence | 1 year | Rate of compliance with device - participants would be asked if they wore the device as advised for the two weeks and adherence would be reported as a percentage. |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORPrachi Mehndiratta, MBBS
University of Maryland, Baltimore
Outcome results
None listed