Breast Cancer Female
Conditions
Keywords
Cognitive Intervention
Brief summary
This study will investigate the benefits of distinct brain health trainings in breast cancer survivors (age 30-80) with cognitive concerns post-chemotherapy. This study can be completed from the comfort of participant's own home.
Detailed description
Participants will complete online assessments at 3 timepoints over 6 months (Month 0, 3, 6). During the first 3 months of the study, participants will be randomized into one of three online training programs to support cognitive function; training will end after the first 3 months. The third online assessment (Month 6) will measure maintained gains since ending training. Participants will not be aware of the interventions assigned to other participants. Participants may be reimbursed for their time.
Interventions
BEHAVIORALBrain Training A
Interventions may include education, exercises, and/or strategies to support brain health
BEHAVIORALBrain Training B
Interventions may include education, exercises, and/or strategies to support brain health
BEHAVIORALBrain Training C
Interventions may include education, exercises, and/or strategies to support brain health
Sponsors
The University of Texas at Dallas
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Female breast cancer survivors who... * are between ages of 30-80 * were diagnosed with Stage I-III * received chemotherapy * completed chemotherapy at least 6 months ago but not more than 5 years * endorse changes in thinking since end of chemotherapy treatment * have working internet and a device * consider themselves fluent in English
Exclusion criteria
* Males * A re-occurrence of breast cancer or a diagnosis of another * An uncorrected hearing or vision issue that would hinder ability to read and/or listen to training material * Participation in a cognitive training program in the last 12 months. * A reported substance abuse problem * Diagnosis of a neurodegenerative disease or psychotic disorder * History of stroke, concussion, or brain injury since completing chemotherapy * Inability to function independently due to Autism Spectrum Disorder diagnosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| BrainHealth Index Score | Baseline, 3 month, 6 month | The investigators will assess change on a holistic measure of cognitive, social, well-being, and daily life health on the BrainHealth Index across multiple timepoints. (Min value = 16, Max value = 1032) (Higher score = Better outcome) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Functional Assessment of Cancer Therapy - Cognitive Function (FACT_Cog) | Baseline, 3 month, 6 month | The investigators will assess change in self-reported cognitive deficits following an online training program. (Min value = 0, Max value = 148) (Higher score = better outcome) |
| Double Decision | Baseline, 3 month, 6 month | The investigators will assess change scores on a visual processing speed task (Min value = 0, Max value = 100) (Higher score = Better performance) |
| Rapid Visual Information Processing | Baseline, 3 month, 6 month | The investigators will assess change scores on measure of selective attention (Min value = 0, Max value = 100) (Higher score = Better performance) |
| Delayed matching to sample | Baseline, 3 month, 6 month | The investigators will assess change scores on measure of visual memory (Min value = 0, Max value = 100) (Higher score = Better performance) |
Countries
United States
Outcome results
None listed