Functional Endoscopic Sinus Surgery
Conditions
Brief summary
Comparison between pregabalin and magnesium sulfate in hypotensive anaethesia
Detailed description
compare the effect of a single-dose 150 mg oral pregabalin and 2 grams intravenous magnesium sulfate given 30 minutes before induction of anesthesia on the total nitroglycerine used in patients undergoing functional endoscopic sinus surgery
Interventions
DRUGPregabalin 150mg
The oral tablet half an hour preoperative 150 milligrams
DRUGMagnesium Sulfate
Intravenous administration half an hour preoperative 2 grams
DRUGNitroglycerin
measure total dose of nitroglycerine in milligrams using a syringe pump
OTHERsurgeon satisfaction
surgeon satisfaction measured according to Likert's scale
Sponsors
Minia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* ASA: class 1 or 2 * Sex: male and female * Age: from 18 to 70 years * Patients scheduled for functional endoscopic sinus surgery
Exclusion criteria
* Patient on diuretics, corticosteroid, pregabalin * Patients with a history of allergy to the study drug * Pregnancy or breastfeeding women Patients with hypertension, cardiac, renal endocrinal diseases * uncooperative patients (cant does not administer oral tablet)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Dose of nitroglycerine | an hour and half | total dose measured by a syringe pump |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| quality of surgical field | an hour and half | using Boezaart et al grading scale |
| surgeon satisfaction | an hour and half | using Likert's scale |
Countries
Egypt
Contacts
Primary ContactEman Gamal, MD
Backup ContactSarah Omar, MD
Outcome results
None listed