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Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning

Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Planning

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05439330
Enrollment
470
Registered
2022-06-30
Start date
2022-09-01
Completion date
2026-12-31
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apical Periodontitis, MRI, Periodontal Inflammation, Retained Tooth, TMJ

Brief summary

The aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional, dental-oriented radiographic images for diagnostic purposes.

Interventions

DEVICEMRI of teeth and surrounding structures

included above

Sponsors

University of Aarhus
Lead SponsorOTHER
Siemens Corporation, Corporate Technology
CollaboratorINDUSTRY
Dentsply Sirona Implants and Consumables
CollaboratorINDUSTRY

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Intervention model description

Each person has a MRI scan done following the requested radiograph. MRI and radiographs are compared for diagnostic purposes.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

(one of the following): * referred for CBCT imaging of at least one tooth for endodontic reasons * referred for intra-oral and/or panoramic imaging covering at least one molar tooth for periodontal reasons * referred for CBCT imaging of the TMJ (bilaterally) * referred for panoramic imaging of the third molar (retained/semi-retained, uni- or bilateral), prior to treatment planning * referred for CBCT imaging prior to implant treatment

Exclusion criteria

* younger than 18 years * unable to give consent * pregnant * pronounced claustrophobia * pacemakers or implanted defibrillators * metal shrapnel injuries of the eyes or MRI incompatible metallic inclusions or implants large tatoos * non-removable piercings

Design outcomes

Primary

MeasureTime frameDescription
Application of a dental-dedicated MRI in the diagnosis of temporomandibular joint disorders, tissue alterations related to third molars, periapical and periodontal inflammatory diseases, and implant treatment planning2½ yearsDiagnosis of pathologies in the TMJ (e.g. disc displacement (anterior/posterior/lateral), inflammation (yes/no), bone changes (yes/no)), periodontal defects (e.g. bone defects (mm), inflammation (yes/no)), periapical pathology (e.g. inflammation (yes/no), apical periodontitis (yes/no)), bone measurements in edentulous areas, and third molars (e.g. relation to surrounding structures (over/same level/under nerve), resorption of neighboring teeth (yes/no)) seen on MRI compared to diagnosis obtained in radiographs. Observations seen on MRI will be compared to observations seen in radiographs.

Countries

Denmark

Contacts

CONTACTRubens Spin-Neto, ph.D
rsn@dent.au.dk+4587159713
STUDY_CHAIRRubens Spin-Neto, ph.D

University of Aarhus

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 5, 2026