A Comprehensive Prospective Assessment of the Physical and Biological Effects of Upper Tract Urothelial Cancer (UTUC)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05438537

Enrollment

300

Registered

2022-06-30

Start date

2021-11-01

Completion date

2030-12-30

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper Tract Urothelial Cancer

Brief summary

There are many controversies and limitations in the management of Upper Tract Urothelial cancer. A prospective registry is set up for patients in our hospital, aim to have a comprehensive prospective assessment of the physical and biological effects of Upper Tract Urothelial cancer in our patients

Detailed description

Although Upper Tract Urothelial Carcinoma (UTUC) is relatively uncommon, the incidence rate is increasing. There are many controversies and limitations in the management of Upper Tract Urothelial cancer. In this study, investigators would like to establish a local registry for upper tract urothelial cancer to facilitate the collection of clinical information and outcomes of upper tract urothelial cancer management, and to collect blood, urine and tumour tissue samples to investigate for new diagnostic and therapeutic agents. Hopefully, our registry can provide information regarding the epidemiology, natural history, and treatment outcomes of upper tract urothelial cancer in Hong Kong.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Male patients \> 18 years old * Patients who has presence of UTUC and pending for surgery * Patients who has history of UTUC with any intervention performed

Exclusion criteria

\- Patients fail to provide informed consent

Design outcomes

Primary

Measure	Time frame	Description
Long-term survival	10 years	Long-term survival

Secondary

Measure	Time frame	Description
Recurrence rate of UTUC	10 years	Recurrence rate of UTUC
Progression rate of UTUC	10 years	Progression rate of UTUC
Complications	10 years	Complications are assessed by medical record and on patient follow up

Countries

Hong Kong

Contacts

CONTACTJeremy Yuen-Chun TEOH, FRCS(Ed)

jeremyteoh@surgery.cuhk.edu.hk3505-2625

PRINCIPAL_INVESTIGATORJeremy Yuen-Chun TEOH, FRCS(Ed) MBBS

Chinese University of Hong Kong

Outcome results