German Inclisiran Network: Retrospective Registry of Patients Being Treated With the siRNA Inclisiran in Germany

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05438069

Acronym

GIN

Enrollment

500

Registered

2022-06-29

Start date

2020-12-11

Completion date

2025-12-11

Last updated

2022-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypercholesterolemia

Brief summary

The German Inclisiran Network is a registry of patients with hypercholesterinemia on treatment with the siRNA inclisiran in Germany

Detailed description

The aim of this retrospective, multi-center analysis is to use individual patient data to determine the extent of the variability in LDL-C reduction in response to inclisiran administration in a real-world setting.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* patients with elevated LDL-C levels (hypercholesterolemia) on stable lipid-lowering drugs for at least one month prior to the application of the siRNA Inclisiran * patients 18 years and older

Exclusion criteria

\- patients who do not qualify for treatment with the siRNA inclisiran according to the G-BA (Gemeinsamer Bundesausschuß) in Germany.

Design outcomes

Primary

Measure	Time frame	Description
LDL-C change	3 months, 6 months, 12 months, 24 months	LDL-C change in mg/dL / mmol/L

Countries

Germany

Contacts

Primary ContactOliver Weingaertner, MD

oliver.weingaertner@med.uni-jena.de+4936419324521

Backup ContactMartin Foerster, PhD

martin.foerster@med.uni-jena.de+4936419325818

Outcome results