Alveolar Bone Loss, Dentin Graft, Ridge Preservation
Conditions
Brief summary
Ridge preservation should be considered whenever possible after tooth extraction. Whether implant placement would be performed or for aesthetic consideration at pontic sites when conventional bridge is planned. Ridge preservation aims to maximize the bone formation accompanied with good soft tissue architecture to facilitate implant and prosthetic replacement restoring function, phonetics and aesthetics. the Aim of the study is To evaluate the bucco-lingual ridge width clinically and radiographically, height of buccal and lingual ridges of the socket after application of injectable platelet rich fibrin and autogenous dentin graft.
Interventions
PROCEDUREinjectable platelet rich fibrin with demineralized dentin graft
after atraumatic extraction, collection of whole venous blood (9 ml) in sterile vacutainer tubes will be done without anticoagulant added, vacutainer tubes will be then placed in a centrifugal machine at 700 revolutions per minute (rpm) for 3 min with a tube filled with water to maintain the balance during the centrifuging process. ADDG particles prepared by demineralization of tooth particles in 0.6N hydrochloric acid for 30 min to achieve demineralization then washed twice in saline and dried with sterile gauze. Graft particles will be loaded at the defect site to restore ridge form, large metal condenser was used to adapt the graft to the defect and stabilizing the graft with sutures.
PROCEDUREdemineralized dentin graft
after atraumatic extraction, ADDG particles will be prepared by demineralization of tooth particles in 0.6N hydrochloric acid for 30 min to achieve demineralization then washed twice in saline and dried with sterile gauze. Graft particles will be loaded at the defect site to restore ridge form, large metal condenser was used to adapt the graft to the defect and stabilizing the graft with sutures.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age ≥ 18 years need of at least one single rooted tooth extraction. * Non-restorable teeth. * Systemically healthy patients. * Good oral hygiene, Plaque index less than 15%. * Non-smoker or Smoking ≤ 10 cigarettes/day. * Cooperative patients able and accept to come for follow up appointments.
Exclusion criteria
* Any interim intervention that may have affected any of the outcomes of interest. * Pregnant and lactation females. * Smoking ˃ 10 cigarettes/day. * Patients reporting systemic conditions that may compromise healing or bone metabolism (eg: diabetes). * Patients with poor oral hygiene. * Any known allergies.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Radiographic Bucco-lingual ridge width change | up to 24 weeks | radiographic measurement |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in the height of the socket buccal and lingual ridges. | up to 24 weeks | radiographic measurement |
| postoperative pain | immediately after the procedure | Visual analogue scale from zero (better) to 10 (worse) |
| Patient satisfaction | immediately after the procedure | binary yes and no |
| Keratinized tissue width | up to 24 weeks | periodontal probe measurement |
| chair time | immediately after the procedure | in minutes |
Countries
Egypt
Outcome results
None listed