Health, Subjective
Conditions
Brief summary
Osteocalcin is a type of vitamin K2-dependent protein, and many studies have confirmed that vitamin K2 has anti-osteoporosis effects, and has preventive and therapeutic effects on a variety of diseases such as nervous system, cardiovascular disease, immune disease, and glucose metabolism. However, as a pleiotropic vitamin and nutrient, vitamin K2 does not have an exact normal range like other vitamins, when it needs to be supplemented, and in what regimen. Different organizations have different opinions on the recommended intake of vitamin K. Thus, this study intends to preliminarily obtain the reference interval of serum vitamin K2 by conducting clinical research in healthy people in the Beijing-Tianjin-Hebei region, and analyzes different factors, such as gender, age, and place of residence, to compare their level differences and changing trends, and to provide data reference for the recommended intake of vitamin K2 for people with vitamin K2 deficiency.
Interventions
None listed
Sponsors
Peking University Third Hospital
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* People aged over 18. * People with normal routine blood test. * Willing to participate in this study.
Exclusion criteria
* Subjects with congenital metabolic problems and endocrine diseases. * Treatment with any investigational drug within the past 3 months.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Concentration of vitamin K2 | During the procedure of regular physical checkups | Vitamin K2 concentration in serum |
Contacts
Primary ContactQi Liu, Ph. D.
Backup ContactChunli Song, M.D.; Ph. D.
Outcome results
None listed