Androgenic Alopecia
Conditions
Brief summary
Patients with Androgenetic alopecia will be randomized into 2 groups; Group FCO2 receiving Fractional CO2 or Group FRF receiving Fractional Microneedling Radiofrequency.
Detailed description
Group FCO2 will be to receiving fractional CO2 to one randomized side of the scalp, and Group FRF will be receiving Fractional Microneedling radiofrequency to one randomized side of the scalp. All patients will receive 4 sessions with 4-week intervals.each session will be followed by immediate topical application of 6 puffs (=1 mL) of minoxidil 5% solution twice daily and also in between the sessions and during follow up period
Interventions
PROCEDUREFCO2
Fractional Carbon dioxide laser
PROCEDUREFRF
Fractional Microneedling Radiofrequency
Sponsors
Kasr El Aini Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* • both genders are included. * Patients above 18 years old.
Exclusion criteria
* • Patients with patchy hair loss. * Patients with Telogen Effluvium or diffuse alopecia areata. * Patients with cicatricial alopecias. * Patients with associated inflammatory scalp disorders such as psoriasis or seborrheic dermatitis. * Patients with collagen vascular disorders. * Prior use of topical steroids on scalp in the previous 2 weeks. * Prior use of systemic steroids in the previous 1 month.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical Global improvement Assessment | 6months-1 year | Photographs will be taken with a Canon camera under controlled light in approximately the same position, taken at baseline, after 4 treatment sessions (16 weeks post treatment) and 2 months after follow-up (24 weeks post treatment). First clinical assessment will be performed based on the clinical change from baseline at 16 weeks post treatment. Change in the clinical will be measured on a 6 point scale; (-1) worsening, (0) no improvement, (1) less than 25% improvement, (2) 25-50% improvement, (3) 50-75% improvement, (4) more than 75% improvement. A higher numerical means a better outcome. |
| Phototrichogram assessment. | months-1 year | A phototrichogram system (Dino-Lite; AnMo Electronics, Taiwan)will be used to evaluate the number of hairs. A higher numerical means a better outcome. |
| Patient satisfaction | 6months-1 year | Participants will be also asked to give their assessment on a scale of 4, (0) no satisfaction (1) slight satisfation, (2) moderate satisfaction, (3) marked satisfaction. A higher numerical means a better outcome. |
Countries
Egypt
Contacts
Primary ContactRana Hilal, MD
Outcome results
None listed