Clinical Performance of Two Cad-cam Fabricated Ceramic Restoration in Teeth Affected With MIH

Clinical Performance of Two CAD/CAM Fabricated Ceramic Restorations With Different Preparation Designs for Rehabilitation Of Permanent First Molars Affected With Molar Incisor Hypomineralisation (MIH): Clinical Randomized Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05434884

Enrollment

Registered

2022-06-28

Start date

2020-07-10

Completion date

2022-03-01

Last updated

2022-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Molar Incisor Hypomineralization

Brief summary

This study will be performed to evaluate the clinical performance (Plaque accumulation, fracture of (restoration or tooth), postoperative sensitivity, secondary caries, marginal fit and discoloration) of two CAD/CAM fabricated ceramic restorations (zirconia-reinforced lithium silicate glass ceramic and hybrid ceramic) with different preparation designs (modified occlusal veneer and endocrown) for rehabilitation of permanent first molars affected with different severity level of molar incisor hypomineralisation (MIH), evaluated at different time periods

Detailed description

Clinical evaluation of all restorations will be performed according to: \- Modified United States Public Health Service (USPHS) Ryge Criteria, at base line (1 week), 3, 6 and 12 months after cementation.

Interventions

PROCEDUREocclusal veneer restorations

occlusal veneer preparation with circumferential chamfer finish line and proximal slot proposed modified occlusal veneer design for rehabilitation of moderate level of permanent first molars. OrPatients will receive endocrown restorations for rehabilitation of sever level of permanent first molars

PROCEDUREendocrown restorations

endocrown restorations

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Intervention model description

Randomized controlled trial (RCT)

Eligibility

Sex/Gender

ALL

Age

8 Years to 13 Years

Healthy volunteers

Yes

Inclusion criteria

- * Patient from 8 to 13 years * permanent first molar tooth affected with different severity levels of MIH * Ability to physically and psychologically tolerate conventional restorative procedures.

Exclusion criteria

. * Patients have active periodontal diseases. * Patient with poor oral hygiene and motivation. * Patient with psychiatric problems or unrealistic expectations

Design outcomes

Primary

Measure	Time frame	Description
retention	1 year	Clinical evaluation of all restorations will be performed according to: \- Modified United States Public Health Service (USPHS) Ryge Criteria,at12 month after cementation
marginal integrity	6 months	Clinical evaluation of all restorations will be performed according to: \- Modified United States Public Health Service (USPHS) Ryge Criteria, at 6 months after cementation
colour stability	12 months	Clinical evaluation of all restorations will be performed according to: \- Modified United States Public Health Service (USPHS) Ryge Criteria, at 12 months after cementation
Elimination of sensitivity	3 months	Clinical evaluation of all restorations will be performed according to: \- Modified United States Public Health Service (USPHS) Ryge Criteria, at 3, months after cementation

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026