CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

The Feasibility of CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05433467

Acronym

CTMH

Enrollment

Registered

2022-06-27

Start date

2022-05-01

Completion date

2026-04-30

Last updated

2025-08-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cirrhosis, Liver, Hepatocellular Carcinoma

Keywords

Cirrhosis, hepatocellular carcinoma, localization needle

Brief summary

In this project, the preoperative anatomical location of micro hepatocellular carcinoma under the guidance of CT can provide guidance for accurate surgical resection. It may also shorten the operation time and reduce intraoperative bleeding.

Detailed description

General and basic information of the patients included in the study was collected. After preoperative preparation was completed, on the day of surgery, disposable pulmonary nodular localization needle (Ningbo Sonjiecang Biological Technology Co., LTD., Model: SS510-10) was used for the localization of micro hepatocellular carcinoma that could be found by preoperative CT enhancement or MRI. After the micro hepatocellular carcinoma was located under the guidance of CT, and then the patient was sent to the operating room. During the operation, the lesion was removed according to the tail line of the positioning needle and the position of the positioning needle.

Interventions

PROCEDURECT-guided localization for micro hepatocellular carcinoma before surgical resection

After preoperative preparation was completed, on the day of surgery, disposable pulmonary nodular localization needle (Ningbo Sonjiecang Biological Technology Co., LTD., Model: SS510-10) was used for the localization of micro hepatocellular carcinoma that could be found by preoperative CT enhancement or MRI. After the micro hepatocellular carcinoma was located under the guidance of CT, and then the patient was sent to the operating room. During the operation, the lesion was removed according to the tail line of the positioning needle and the position of the positioning needle.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Be at least 18 years old and give informed consent to participate in the study 2. A preoperative (clinical, radiological, or histological) diagnosis of cirrhosis of the liver due to any cause. 3. micro hepatocellular carcinoma (diameter less than 1cm). 4. Preoperative CT plain scan could not find the lesion, and preoperative B-ultrasound could not find the lesion. 5. Preoperative CT enhancement or MRI can detect the lesion.

Exclusion criteria

1. Child-Pugh grade C 2. Uncontrolled Hypertension 3. Severe lung dysfunction 4. Severe cardiac dysfunction

Design outcomes

Primary

Measure	Time frame	Description
The position of the needle	During operation	The distance (mm) of the needle to the edge of hepatocellular carcinoma

Secondary

Measure	Time frame	Description
Operation time	During operation	The length of operation time (min)
Intraoperative bleeding	During operation	The volume of intraoperative bleeding (ml)

Countries

China

Contacts

Primary ContactGuo-Qing Jiang, MD

jgqing2003@hotmail.com+8651487373382

Backup ContactDou-Sheng Bai, MD