Pain, Postoperative Pain, Acute Pain, Analgesia, Hip Arthropathy, Postoperative Complications
Conditions
Brief summary
This study aims to analyze the effect of Pericapsular Nerve Group (PENG) Block combined with lateral femoral cutaneous nerve block vs. PENG block combined with wound infiltration for analgesia after elective hip replacement performed with a posters-lateral approach. Half of participants will receive a PENG Block combined with femoral lateral cutaneous nerve block, while the other half will receive PENG Block combined with wound infiltration
Interventions
PROCEDUREPENG Block
At the end of surgery, in Post Anesthesia Recovery Room (PACU), PENG block with 20 mL of 0.5 % Ropivacaine will be executed as described by Giron-Arango et al. using a low frequency curvilinear probe. A 22G 80 mm needle (Stimuplex Ultra 360, B.Braun) will be used.
At the end of surgery, in Post Anesthesia Recovery Room (PACU), ultrasound guided Lateral Femoral Cutaneous Nerve Block will be performed with 10 mL of 0.5 % Ropivacaine using a high frequency linear probe. A 22G 50 mm needle (Stimuplex Ultra 360, B.Braun) will be used.
PROCEDUREWound Infiltration
At the end of operation, the surgeon will perform wound infiltration with 20 mL of 0.5 % Ropivacaine.
Sponsors
Campus Bio-Medico University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Elective hip replacement surgery performed with a poster-lateral approach * ASA physical status score \< 4
Exclusion criteria
* Contraindications to regional anesthesia * ASA physical status score ≥ 4 * Patient's refusal or inability to sign the informed consent * Allergies to any drug provided by the study protocol
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Static Pain Score | 24 hours | A numerical rating scale (NRS) from 0 (no pain) to 10 (worst imaginable pain) will be used to evaluate pain at rest during 24 hours after surgery |
| Dynamic Pain Score | 24 hours | A numerical rating scale (NRS) from 0 (no pain) to 10 (worst imaginable pain) will be used to evaluate pain on movement during 24 hours after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quadriceps Strength | 24 hours | Ability to flex the knee against gravity |
| Ability to start physiotherapy during the first postoperative day | 24 hours | YES: the patient was able to start physiotherapy NO: the patient was not able to start physiotherapy during the first postoperative day due to pain or motor block |
| Morphine consumption | 24 hours | Total of intravenous morphine (expressed in milligrams) administered during the first 24 hours after surgery |
| Incidence of block complications | 24 hours | Any complications or side effects of the blocks, such as local infection, intravascular injection of local anesthetics and immediate systemic toxicity. Moreover, incidence of nausea, vomiting and postoperative respiratory depression will be recorded |
| Hospital Length of Stay | 6 days | Total Hospital length of Stay (expressed in days) |
| Ability to ambulate with the help of a walker during the first postoperative day | 24 hours | YES: The patient was able to ambulate with the help of a walker NO: The patient was not able to ambulate with the help of a walker due to pain or motor block |
| Range of hip motion | 24 hours | Degrees of hip flexion |
Countries
Italy
Outcome results
None listed