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Evaluation of Corneal Endothelial Changes After Uneventful Phacoemulsification in Diabetic and Non-diabetic Patients in Relation to the Level of Glcosylated Hemoglobin Level

Evaluation of Corneal Endothelial Changes After Uneventful Phacoemulsification in Diabetic and Non-diabetic Patients in Relation to the Level of Glcosylated Hemoglobin Level

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05426590
Enrollment
68
Registered
2022-06-22
Start date
2022-05-20
Completion date
2022-11-17
Last updated
2022-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal Endothelial Changes After Phacoemulsification

Brief summary

Evaluation of corneal endothelial changes after uneventful phacoemulsification in diabetic and non-diabetic patients using specular biomicroscopy in relation to the level of glcosylated hemoglobin level

Detailed description

86 patients will be divided into two equal groups of diabetic and non-diabetic patients will undergo phacoemulsification of cataract will be evaluated thier endocelium before surgery and 3 weeks after surgery to detect the effect of level of glcosylated hemoglobin on the endothelial changes after uneventful phacoemulsification

Interventions

DEVICESpecular biomicroscopy

Specular microscopy will be done before and 3 weeks after cataract surgery

Sponsors

Marwa Ahmed
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
50 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Diabetics and non-diabetic patients undergo cataract surgery * Age between 50-60 years old * Corrected distance visual acuity\<0.4 * Gender: both genders.

Exclusion criteria

* Chronic Ocular diseases (glaucoma,uveitis, amblyopia, strabismus,keratoconus, corneal opacity). * corneal dystrophy History of previous keratitis or viral corneal infection. Corneal dystrophy Ocular trauma. Previous ocular surgery. Complicated cataract surgery

Design outcomes

Primary

MeasureTime frameDescription
Defferentiate patients into diabetic and non-diabetic patients according to the endothelial changes after uneventful phacoemulsification6 monthesDetect effect of glycosylated hemoglobin level after uneventful phacoemulsification in diabetic and non-diabetic patients

Countries

Egypt

Contacts

Primary ContactMarwa A Abdelaal
Magicoromi@gmail.com01129875785
Backup ContactMohamed A Hosney
Mohamedhosny@kasralainy.edu.eg01000007676

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026