Near-Sudden Unexpected Death in Epilepsy, Sudden Unexpected Death in Epilepsy
Conditions
Brief summary
Sudden unexpected death in epilepsy (SUDEP) is regarded as a leading cause of premature death in epilepsy patients. We aim to capture the whole process of SUDEP and near-SUDEP occurrence in patients with epilepsy, and expolre video-electroencephalograph (V-EEG) changes and marker. A Chinese multicenter study was carried out to determine electroencephalo-graph marker related to SUDEP to provide a scientific basis for the prevention of SUDEP in patients with epilepsy.
Interventions
DIAGNOSTIC_TESTVideo-Electroencephalography
Three types of video EEG monitoring equipment produced by Nicolet, Bio-logic and Nihon Kohden were used to collect data in the multi-center. The 19-lead recording electrode was placed according to the international 10-20 system, and the average lead was used. The recording time was 24h. All patients underwent eyes open and closed test, intermittent photic stimulation and hyperventilation induction test.
Sponsors
Liu Yonghong
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients with epilepsy who meet SUDEP or near-SUDEP diagnosis, * Giving written informed consent to participate in the study from relatives or caregivers.
Exclusion criteria
* Refusing to recruitment from relatives or caregivers.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The occurrence of SUDEP or near-SUDEP | 2022.04.01-2024.04.01 | Baseline, clinical characteristics and EEG markers of SUDEP patients were collected. |
Countries
China
Outcome results
None listed