Long-term Outcomes After Laparoscopic Subtotal and Total Hysterectomy

Evaluation of Long-term Sexual Dysfunctions, Urinary Dysfunctions and Pelvic Organ Prolapse in Women Who Underwent Laparoscopic Subtotal Versus Total Hysterectomy for Benign Conditions

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05421156

Acronym

LAST-1

Enrollment

100

Registered

2022-06-16

Start date

2024-07-31

Completion date

2028-07-31

Last updated

2022-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysterectomy

Keywords

Subtotal Laparoscopic Hysterectomy, Total Laparoscopic Hysterectomy, Hysterectomy

Brief summary

Hysterectomy is one of the most commonly performed gynecologic surgeries in the USA. It is used for many benign conditions such as leiomyoma and abnormal uterine bleeding. Surgery may involve the removal of the cervix (total hysterectomy, TH) or its preservation (supracervical or subtotal hysterectomy, SH). Whether TH or SH is the best procedure for benign conditions is a matter of debate. Considering the lack of evidence, this study aims to evaluate long-term sexual dysfunctions, urinary dysfunctions and pelvic organ prolapse in women who underwent laparoscopic subtotal versus total hysterectomy for benign conditions.

Interventions

PROCEDURESubtotal Laparoscopic Hysterectomy

Subtotal laparoscopic hysterectomy involves removing the main body of the uterus and leaving the cervix in place by laparoscopy.

PROCEDURETotal Laparoscopic Hysterectomy

Total laparoscopic hysterectomy involves removing the whole uterus and cervix by laparoscopy

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Women who underwent subtotal or total hysterectomy by laparoscopy for benign conditions.

Exclusion criteria

* Women with gynecological and non-gynecological cancers.

Design outcomes

Primary

Measure	Time frame	Description
Sexual Dysfunctions	5 years after surgery	Female Sexual Function Index

Secondary

Measure	Time frame	Description
Urinary Dysfunctions	5 years after surgery	Pelvic Floor Distress Inventory short form
Pelvic Organ Prolapse	5 years after surgery	Pelvic Organ Prolapse (POP-Q) evaluation

Contacts

Primary ContactAntonio Simone Laganà, M.D., Ph.D.

antoniosimone.lagana@unipa.it3296279579

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026