Burns
Conditions
Brief summary
This study aimed to optimize fluid resuscitation with transpulmonary thermodilution (TPTD)-guided protocol and to lower the mortality rate of the severely burned.
Interventions
The control group included patients being admitted when TPTD device was unavailable; and relatively stable patients without the need for TPTD. The adequacy of fluid resuscitation in the control group was monitored by traditional monitoring parameters including vital signs and hourly urine output.
TPTD device was implemented for monitoring; the inclusion criteria included patients suffering from 2nd degree burn greater than 40% TBSA; a combined 2nd to 3rd degree burn greater than 30% TBSA; or patients with inhalation injury despite the burned surface area.
Sponsors
Study design
Eligibility
Inclusion criteria
* Adult patients (age \> 18 years). * Major burn (as total burned surface area (TBSA) \> 20% with at least second degree burn depth). * Admitted to the intensive care unit (ICU) of the Burn Center.
Exclusion criteria
* Patients younger than 18 years old. * Patients with severe cardiopulmonary diseases, or associated with other major trauma. * Patient with incomplete data.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patient mortality | Up to 6 months | The primary outcome was patient mortality after major burn. |
Countries
Taiwan