Clinical Assessment of 3 Differant Obturation Sealers on Postoprative Pain and Swelling

Assessment of 3 Different Root Canal Obturating Sealers on Postoperative Pain and Swelling in Single Canal Necrotic Teeth With a Single Visit .a Randomized Controlled Trial

Status

UNKNOWN

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05419752

Enrollment

Registered

2022-06-15

Start date

2022-07-30

Completion date

2022-08-30

Last updated

2022-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Necrotic Pulp, Single Root Teeth

Brief summary

aim of the study will be conducted to compare the effect of MTA fill apex sealer and endo sequence bioceramic sealer in obturation on the intenisty of postoperative pain and the incidence of post operative swelling in patient with necrotic teeth .

Interventions

DRUGbioceramic sealer

bioceramic based obturating sealer

DRUGMTA

MTA based obturating sealer

DRUGresin sealer

resin based obturating sealer

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients requiring root canal treatment of single canal necrotic teeth. * Patient from 18 to 60 years old * Patients with Asymptomatic apical periodontitis. * Teeth presenting with no clinical symptoms and with a periapical score from 2 to 4 according to Orstavik et al

Exclusion criteria

* Teeth with incompletely formed apex * Teeth requiring retreatment * Patients having complicating systemic disease such as diabetes, malignancy, pregnancy, central nervous system disorders, Cardiovascular system disorders, respiratory disorders, asthma patients, psychiatric disorders, immunocompromised patients * Patients taking anti-inflammatory or antibiotics * Patients giving history of analgesic or antibiotic intake 1 week before treatment * Patients below 18 years of age * Patients above 65 years of age * Patients having history of peptic ulcer or gastrointestinal bleeding * Teeth affected with periodontal disease

Design outcomes

Primary

Measure	Time frame	Description
Intensity of post-operative pain	6 hours	Measurement of post-operative pain by Visual analogue scale

Secondary

Measure	Time frame	Description
post operative swelling	24 hours	Yes or no yes or no

Contacts

Primary ContactElsayed Hany Elmasry, bsc

elsayed.hany@dentistry.cu.edu.eg00201159536873

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026