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Prognostic Value of Pediatric GCS-Pupil Score in Pediatric Patients With Traumatic Brain Injury

Prognostic Value of Pediatric GCS-Pupil Score in Pediatric Patients With Traumatic Brain Injury

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05419739
Enrollment
128
Registered
2022-06-15
Start date
2022-07-31
Completion date
2023-07-31
Last updated
2022-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Injuries, Traumatic

Keywords

Brain traumatic, GCS-Pupil score, Pediatric

Brief summary

There are studies reporting that the survival rate in pediatric patients with abnormal pupillary response is 23% and that pupillary response is effective on mortality and patient outcomes. Studies in the literature examining the effect of pupillary response on mortality and outcome in pediatric patients with traumatic brain injury reported that bilaterally dilated pupils were associated with a higher mortality rate. Considering the literature results, we believe that obtaining the GCS-Pupil score by combining GCS and pupillary reaction in pediatric patients with traumatic brain injury will be effective in predicting patient outcomes.

Detailed description

Obtaining a GCS-Pupil score using the total GCS score: 0 points are given for pupillary reaction if both pupils react to light, 1 point if one pupil does not react to light, and 2 points if both pupils do not react to light. Total GCS-P score is calculated by the formula of Eye Response + Verbal Response + Motor Response - Pupil Reaction and scores between 1-15. In the study, the worst GCS and current pupillary light reaction score in the first 24 hours will be evaluated.

Interventions

This scale, which consists of three parameters, includes the best eye response (1-4 points), the best verbal response (1-5 points), and the best motor response (1-6 points). Total score; It is calculated as Eye Response + Verbal Response + Motor Response and takes a value between 3-15 points. The severity of head trauma is evaluated in three categories: mild (GCS 13-15 points), moderate (GCS 9-12 points), and severe (GCS ≤ 8 points).

Sponsors

Uludag University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No

Inclusion criteria

* Be under the age of 18, * Not having mental and motor developmental retardation, * Having had a traumatic brain injury, * Alive at admission and followed up for at least 24 hours

Exclusion criteria

* Eye trauma or severe facial trauma that will affect the assessment, * Those under deep sedation, * Those who have been administered drugs (Atropine and mydriatic) that will affect the pupillary response.

Design outcomes

Primary

MeasureTime frameDescription
Death rateone yearDeath

Secondary

MeasureTime frameDescription
Adverse functional outcomesone yearseverely crippled or vegetative condition

Countries

Turkey (Türkiye)

Contacts

Primary ContactAKİF BULUT, MSc
akifblt23@gmail.com+90 546 872 28 72

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026