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Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy

Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05417672
Enrollment
63
Registered
2022-06-14
Start date
2021-09-29
Completion date
2022-09-01
Last updated
2022-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer, Malnutrition, Nutritional Deficiency

Brief summary

Malnutrition is common in patients with lung cancer. In patients with malnutrition risk, the risk of complications is high both in the perioperative, early and late postoperative periods. Malnutrition is an independent risk factor for length of hospital stay and cost in these patients. Patients with lung cancer may have many morbidities in postoperative period, especially problems with wound healing. Therefore, assessment of the nutritional status of patients with lung cancer should begin at the diagnosis stage.

Detailed description

In patients with lung cancer scheduled for lobectomy, anthropometric measurements will be measured and the results of laboratory tests(albumin, prealbumin, creatinine, total lymphocyte count, C reactive protein), Nutritional Risk Screening-2002, Nutritional Risk Index, Mini Nutritional Assessment, Glasgow Prognostic Score, Prognostic Nutritional Index and neoadjuvant chemotherapy or not will be recorded in 72 hours before surgery. In addition, demographic information of the patients (name, surname, identification number, age, comorbidity, American Society of Anesthesiologists score) will be recorded. After the information is given to the patients, their written and verbal consent will be obtained. In the operating room, routine monitoring (electrocardiography, invasive blood pressure measurement, arterial blood gas monitoring, peripheral oxygen saturation, end-tidal carbon dioxide measurement by capnography) will be applied to the patients in accordance with the standard protocol for elective lobectomy surgery. Hemodynamic changes (eg. dysrhythmia, hypotension, hypertension, hemorrhage), metabolic status (pH, bicarbonate, base excess), lactate, glucose level in blood gas evaluation and intraoperative complications will be recorded during the intraoperative period. In the postoperative period, length of stay in the intensive care unit, length of hospital stay, early complications (eg. dysrhythmia, acute coronary syndrome, sepsis, mediastinitis, pneumonia, surgical site infection, prolonged air leak), time to start oral intake and transition to adequate oral intake will be recorded in the one-month postoperative period.

Interventions

DIAGNOSTIC_TESTNutritional Risk Screening-2002

Nutritional Risk Screening-2002

DIAGNOSTIC_TESTNutritional Risk Index

Nutritional Risk Index

DIAGNOSTIC_TESTMini Nutritional Assessment

Mini Nutritional Assessment

DIAGNOSTIC_TESTGlasgow Prognostic Score

Glasgow Prognostic Score

Prognostic Nutritional Index

middle arm circumference

Handgrip strength test

Sponsors

Turkish Society of Anesthesiology and Reanimation
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Having a diagnosis of lung cancer * Lung lobectomy operation will be performed * 18 years and older patients * Having an American Society of Anesthesiologists score of 1, 2, 3 * Having approved and signed the informed consent form

Exclusion criteria

* Patients who underwent lobectomy with a diagnosis other than lung cancer * Patients younger than 18 years * Patients with an American Society of Anesthesiologists score of 4 and above * Patients who did not accept informed consent * Patients who refused to participate in the study

Design outcomes

Primary

MeasureTime frameDescription
Postoperative complicationsa month after the surgerydysrhythmia, acute coronary syndrome, sepsis, mediastinitis, pneumonia, surgical site infection, prolonged air leak
Length of stay in the intensive care unitup to 30 daysLength of stay in the intensive care unit
Length of hospital stayup to 30 daysLength of hospital stay
Intraoperative hemodynamic complicationsduring the proceduredysrhythmia, hypotension, hypertension, hemorrhage

Secondary

MeasureTime frameDescription
lactateduring the procedurelactate level in arterial blood gas evaluation
Oral intakeup to 30 daystime to start oral intake and transition to adequate oral intake
glucoseduring the procedureglucose level in arterial blood gas evaluation
pHduring the procedurepH in arterial blood gas evaluation
bicarbonateduring the procedurebicarbonate level in arterial blood gas evaluation
base excessduring the procedurebase excess in arterial blood gas evaluation

Countries

Turkey (Türkiye)

Contacts

Primary ContactSeda Eğilmez
egilmezseda@gmail.com905063564052
Backup ContactNermin Kelebek Girgin
nerminkelebek@yahoo.com905323875956

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026