Lasers in Onychomycosis

Comparison Between Different Types of LASER in the Treatment of Onychomycosis, a Randomized Controlled Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05415852

Enrollment

Registered

2022-06-13

Start date

2022-06-25

Completion date

2022-09-15

Last updated

2022-06-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Onychomycosis

Brief summary

Onychomycosis is the most common nail disease, representing more than 50% of all onychopathies. Future studies on the absorption spectra of dermatophyte fungi will be needed to develop lasers that effectively exploit absorption differences in fungi and dermal tissue.

Detailed description

Treatments with antifungals may not be successful due to several factors, including the long time required to apply topical medications, the side effects of systemic drugs, and the application of insufficient medication to the target area. Even with adequate systemic or topical therapy, the persistence of fungal infections is not uncommon. In light of these limitations, laser therapy has been proposed as an alternative option for onychomycosis therapy.

Interventions

DEVICELaser

Laser

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Patients with onychomycosis.

Exclusion criteria

* Patients with excessive manual work

Design outcomes

Primary

Measure	Time frame	Description
Onychomycosis severity index	change from baseline at 3 months	clinical assessment

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026