Cardiovascular Diseases, Heart Attack
Conditions
Brief summary
The goal of this pilot study is to use total body PET/CT imaging to examine the relationships between stress, amygdala activation, and arterial wall inflammation in participants before and after participating in a multi-modal stress reduction program.
Interventions
This is a multimodal mind-body program designed to teach participants a variety of different strategies to reduce their physiologic stress response.
Sponsors
University of California, Davis
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Concurrently enrolled in an observational study of patients who have had an acute myocardial infarction * Score on PSS-10 of 14 or greater during screening * Willing and able to access the internet to participate in the online SMART Program
Exclusion criteria
* Poorly controlled physical or mental health condition that would likely interfere with the ability to participate in SMART or ability to undergo PET scan * Current daily practice of meditation of 10 minutes or more per day
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in amygdala activation | about 10 weeks | change in radiotracer uptake in the amygdala with FDG-PET imaging from before to after the SMART Program |
Countries
United States
Outcome results
None listed