Wrist Osteoarthritis
Conditions
Brief summary
This study plans to learn more about the effect of adding tissue graft for wrist osteoarthritis reconstruction procedures. Previous studies have shown better allograft stability, and no documented foreign body reaction than with silicone and other synthetic materials.
Interventions
PROCEDUREMeniscus Allograft Transplantation with Proximal Row Carpectomy
Supplementing the wrist reconstruction with a meniscal allograft to improve wrist function and pain scores.
PROCEDUREProximal Row Carpectomy
Standard proximal row carpectomy with no tissue or synthetic adjuncts
Sponsors
University of Colorado, Denver
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* symptomatic wrist arthritis associated with SLAC or SNAC pathology * Patients 30 years or older or 80 years or younger
Exclusion criteria
* Patients younger than 29 years or older than 80 years * History of previous surgery related to wrist osteoarthritis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 24 months | 24 months | Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question. |
| DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 6 months | 6 months | Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question. |
| DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 9 months | 9 months | Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question. |
| DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 12 months | 12 months | Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question. |
| DISABILITIES OF THE ARM, SHOULDER AND HAND Score: Baseline/Pre-op | Preoperatively | Participant wrist disability score will be assessed before and after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question. |
| DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 2 weeks | 2 weeks | Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question. |
| DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 6 weeks | 6 weeks | Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question. |
| DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 3 months | 3 months | Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Radiographic joint spacing | 3 months, up to 24 Months | Measurement of joint spacing in the wrist in millimeters. |
| MRI Joint Spacing | 9 Months, 24 Months | Wrist joint spacing measurements in millimeters using Magnetic resonance imaging (MRI) |
| Pain Score | Preoperatively, up to 24 Months | Visual Analog Pain Score |
Countries
United States
Contacts
Primary ContactFraser J Leversedge, MD
Backup ContactEmma Judge
Outcome results
None listed