Healthy, Hypertension, Sleep Disorder
Conditions
Brief summary
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
Interventions
DIAGNOSTIC_TEST24 hour blood pressure (BP) monitoring
24-hour ambulatory BP measuring device and blood pressures will be measured every 20 minutes to half hour
DIAGNOSTIC_TESTPolysomnography
Measurements will include electroencephalogram, electromyogram, electrooculogram, electrocardiogram, breathing patterns of chest and abdomen, nasal and oral airflow and oxygen saturation. Sleep stages and apneas will be scored in accordance with validated American Academy of Sleep Medicine standards.
Sponsors
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI)
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Subjects diagnosed with no known history of hypertension, diabetes, or sleep disorders. * Self-identify as Somali. * Adult males and females who are older than 18 years of age.
Exclusion criteria
* Anyone under 18 years or over 70 years. * Positive pregnancy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Undiagnosed sleep deficiency-short sleep | 1 night sleep study, approximately 8-9 hours | Number of subjects to have short sleep (\<6 hours) as measured by the sleep study |
| Undiagnosed sleep deficiency-insomnia | 1 night sleep study, approximately 8-9 hours | Number of subjects to have insomnia as measured by the sleep study |
| Undiagnosed sleep deficiency-obstructive sleep apnea (OSA) | 1 night sleep study, approximately 8-9 hours | Number of subjects to have OSA as measured by the sleep study |
| Disrupted sleep | 1 night sleep study, approximately 8-9 hours | Number of subjects to have disrupted sleep as measured by the sleep study |
| Blood pressure (BP) during wakefulness | Day 2 | Average BP as measured by 24 hour BP monitoring, reported in mmHg |
| Blood pressure (BP) during sleep | Day 2 | Average BP as measured by 24 hour BP monitoring, reported in mmHg |
Countries
United States
Contacts
CONTACTSomers CPL Lab
PRINCIPAL_INVESTIGATORVirend Somers, MD
Mayo Clinic
Outcome results
None listed