Varicose Vein in Patients Under the Age of 40

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05410912

Enrollment

168

Registered

2022-06-08

Start date

2021-01-01

Completion date

2024-12-30

Last updated

2024-09-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Varicose Veins

Brief summary

Varicose veins are a result of valvular insufficiency and presented with twisted, enlarged veins. They not only cause cosmetic concerns but also lead to limb edema, skin pigmentation/lipodermatosclerosis, and even venous ulcers. This disease affects a large percentage of the population. Although there have been several researches on the risk factors for varicose veins and the outcomes of alternative therapies , there is currently limited data focusing on varicose veins in young patients. In this case-control study, we wanted to assess the risk factors for varicose veins in patients under the age of 40, as well as their long-term results of surgery.

Interventions

PROCEDUREGreat saphenous vein stripping and ambulatory phlebectomy

All patients included in the study were treated with great saphenous vein stripping and ambulatory phlebectomy.

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. great saphenous varicose veins (GSVV) with saphenous vein reflux \>0.5s. 2. lower extremity venography excluding iliac vein compression; 3. treated by great saphenous vein stripping and ambulatory phlebectomy. 4. the patient had a minimum follow-up of five years.

Exclusion criteria

1. secondary varicose veins (defined as varicose veins caused by deep vein thrombosis, iliac venous compression or venous injury etc.); 2. small saphenous veins; 3. treated by endovenous ablation/laser or sclerotherapy alone.

Design outcomes

Primary

Measure	Time frame	Description
Postoperative varicose veins sequelae	Five years after surgery.	The sequelae of the varicose vein were assessed by Venous Clinical Severity Score (VCSS). The total score is 0\ 30. The higher scores mean a worse outcome.
Postoperative quality of life	Five years after surgery.	Quality of life was assessed by the Aberdeen Varicose Vein Questionnaire (AVVQ). The total score is 1\ 100. The higher scores mean a worse outcome.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026