Ovarian Cancer
Conditions
Brief summary
In this study, mass spectrometry was used to analyze immune inflammation-related protein complexes, post-translational modified glycopeptide omics and tumor-related metabolomics in serum, respectively, in order to find potential metabolic small molecule biomarkers or marker profiles that can be used for early diagnosis of cancer recurrence.
Detailed description
Time cohort study: patients with confirmed ovarian epithelial cancer at different time cutoff points before treatment, after surgery, during chemotherapy, and after chemotherapy, until clinically confirmed patients relapse. At least 50 patients are expected to be enrolled.
Interventions
OTHERNo intervention in clinical treatment
No intervention in clinical treatment
Sponsors
Peking Union Medical College Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Female * A diagnosed patient with epithelial ovarian cancer * Age ≤ 70
Exclusion criteria
* Male * Suffering from other malignant tumors * Non-compliant patient * Age above 70
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Immune Inflammation-Related Protein Complexes | 2 years | The change of immune inflammation-related protein complexes |
Countries
China
Contacts
Primary ContactPeng Peng, MD
Outcome results
None listed