Coronary Artery Disease
Conditions
Keywords
Carotid Artery Ultrasound, Carotid Plaque, Coronary Artery Disease
Brief summary
This multicenter study involved 5 hospitals (Changhai Hospital; Yueyang Hospital of Shanghai University of Traditional Chinese Medicine; Gongli Hospital; Putuo Hospital of Shanghai University of Traditional Chinese Medicine; No. 904 Hospital of the PLA Joint Logistics Support Force Wuxi). The study enrolled 3000 patients for suspected CAD who referred to coronary angiography from January 2017 through December 2018.
Detailed description
Patients with coronary artery disease who were confirmed by coronary angiography were eligible for the study. Carotid ultrasonography was performed before coronary angiography, and carotid intima-media thickness (IMT), maximum thickness and length of all plaques were measured.
Interventions
None listed
Sponsors
Putuo Hospital, Shanghai University of Traditional Chinese Medicine
904th Hospital of the Joint Logistics Support Force of the PLA
Gongli Hospital
Yueyang Hospital, Shanghai University of Traditional Chinese medicine
Changhai Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients≥18 years old, those who underwent carotid ultrasonography and first coronary angiography simultaneously.
Exclusion criteria
* Patients with known coronary artery disease, previous coronary or carotid revascularization, missing carotid ultrasound or coronary angiography results.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| major cardiovascular event | 3 years | A composite of cardiovascular death, myocardial infarction, and ischemic stroke |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| all-cause death | 3 years | — |
| cardiovascular death | 3 years | — |
| major vascular event | 3 years | A composite of cardiovascular death, myocardial infarction, ischemic stroke, and coronary artery revascularization |
| ischemic stroke | 3 years | — |
| coronary artery revascularization | 3 years | coronary artery bypass grafting or percutaneous coronary intervention |
| myocardial infarction | 3 years | — |
Countries
China
Outcome results
None listed