Skip to content

Postoperative Cognitive Dysfunction in Heart Surgery

Postoperative Cognitive Dysfunction in Participants Undergoing Open Heart Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05406843
Enrollment
140
Registered
2022-06-07
Start date
2020-01-01
Completion date
2021-08-01
Last updated
2022-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Cognitive Dysfunction

Keywords

COGNITIVE DYSFUNCTİON, HEART SURGERY, POSTOPERATIVE DELIRIUM

Brief summary

To determine the rate of Postoperative Cognitive Dysfunction (POCD) in the early and late postoperative periods by comparing the preop and postop period mini mental status tests in participants undergoing open heart surgery, and to compare the results of the investgators clinic with the world literature.

Detailed description

Postoperative delirium (POD) and Cognitive Dysfunction (POCD) are changes in mental status, especially in the geriatric surgery population.Unlike other forms of delirium, POD results in early full recovery.Postoperative Cognitive Dysfunction (POCD) is more difficult to define and implies temporal consciousness impairment associated with surgery. While the diagnosis of delirium requires the detection of symptoms, the diagnosis of POCD requires preoperative neuropsychological testing and determining how much reduction will mean cognitive dysfunction. Postoperative delirium management is complex and requires multiple strategies. Methods of treating and preventing POCD are still uncertain.It is known that POCD is most commonly seen in patients undergoing open heart surgery.In this study, the investigators aim is to evaluate whether there is any change in cognitive status in the postoperative period compared to the preoperative period of participants who will undergo open heart surgery due to valve pathology or coronary stenosis.

Interventions

OTHERPreoperative cognitive functions of participants undergoing open heart surgery

Surgery times and cross-clamping times of the participants who will undergo open heart surgery were recorded.

OTHERPostoperative cognitive functions of particiants undergoing open heart surgery

Changes in mini mental test scores were recorded in the postoperative period.

Sponsors

Kocaeli University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* 18-75 age * American Society of Anesthesiologists (ASA) II-III

Exclusion criteria

* \>75 age * \<18 age * Patients who died within 48 hours after the operation

Design outcomes

Primary

MeasureTime frameDescription
Evaluation of postoperative cognitive functions in participants undergoing open heart surgery.1 yearThe aim is to understand whether there is a loss of cognitive functions in the postoperative period, according to the preoperative periods, by testing the participants with open heart surgery on the 3rd day, 7th day, and 2nd month after the surgery.

Secondary

MeasureTime frameDescription
Comparison with the literature.1 yearComparison of the results in the investigators clinic with the literature.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026