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Machine Learning to Reduce Hypertension Treatment Clinical Inertia

Machine Learning to Reduce Hypertension Treatment Clinical Inertia

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05406336
Enrollment
50
Registered
2022-06-06
Start date
2025-04-25
Completion date
2025-07-31
Last updated
2025-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Keywords

Uncontrolled blood pressure, Antihypertensive medication, Hypertension treatment, Clinical inertia, Machine learning

Brief summary

Among individuals with an uncontrolled BP at the current visit, the objective of this study is to compare clinical management of hypertension with and without information from a machine learning algorithm on whether a patient will have uncontrolled blood pressure at their next follow up visit through a case-vignette study.

Detailed description

Among adults with uncontrolled blood pressure (BP) at a clinic visit, clinical inertia is common. Clinical inertia is defined as a failure of providers to initiate or intensify treatment (i.e., adding medication or increasing dosage) when guidelines indicate doing so. Prior studies report that clinicians intensify antihypertensive medication treatment in less than 20% of visits where intensification would have been clinically recommended. Thus, patients who have uncontrolled BP may not receive timely therapy to control their BP. To address this issue, the investigators will use a randomized design to test the hypothesis that clinicians will be more likely to intensify the hypertensive regimen and/or assess nonadherence for patients with uncontrolled BP at the current visit when presented with information that a patient is predicted to have uncontrolled BP at the next visit by a machine learning algorithm.

Interventions

OTHERPredicted uncontrolled BP status (yes/no) at follow up visit, derived using a machine learning algorithm

The investigators have created a machine learning algorithm to predict uncontrolled blood pressure (BP) status (yes/no) at a follow up visit among adults with uncontrolled BP at their current visit. The investigators will determine whether adding this information to a vignette describing a patient will increase the likelihood that a clinician will intensify antihypertensive medication treatment.

Sponsors

Temple University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

practicing primary care clinicians who see patients (i.e., internal medicine, family medicine, attending physicians, nurse practitioners) will be eligible to participate -

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Vignette #1 - antihypertensive medication treatment intensificationImmediately after clinical vignetteA clinical vignette of a patient with uncontrolled blood pressure will be presented to clinicians. They will then be asked to assess wether they would intensify antihypertensive medication treatment. This will be assessed using a 5-point Likert scale with scores ranging from 1 (Strongly disagree) to 5 (Strongly agree). Likert scale scores will be compared between clinicians in the control and intervention group.
Vignette #2 - antihypertensive medication treatment intensificationImmediately after clinical vignetteA second clinical vignette of a patient with uncontrolled blood pressure will be presented to clinicians. They will then be asked to assess wether they would intensify antihypertensive medication treatment. This will be assessed using a 5-point Likert scale with scores ranging from 1 (Strongly disagree) to 5 (Strongly agree). Likert scale scores will be compared between clinicians in the control and intervention group.
Vignette #3 - antihypertensive medication treatment intensificationImmediately after clinical vignetteA third clinical vignette of a patient with uncontrolled blood pressure will be presented to clinicians. They will then be asked to assess wether they would intensify antihypertensive medication treatment. This will be assessed using a 5-point Likert scale with scores ranging from 1 (Strongly disagree) to 5 (Strongly agree). Likert scale scores will be compared between clinicians in the control and intervention group.

Contacts

Primary ContactGabriel Tajeu, DrPH
gtajeu@uab.edu2055312258

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026