Analgesia
Conditions
Brief summary
The aim of this study is compare the efficacy of local anesthetic infiltration into all layers of the anterior abdominal wall and peritoneal instillation and intrathecal injection of morphine with local anesthesic to reduce pain in women undergoing elective cesarean section under spinal anesthesia. The primary outcome is to compare the total amount of opioids consumed in the first 24 hours postoperatively. Secondary purpose; Pain scores at 2,4,6,12,and 24 hours during movement ( moving back and forth in bed ) and rest ( lying motionless in bed )
Detailed description
This prospective randomized double-blind study will be planned on 46 pregnant women aged 18-50 who will undergo cesarean section with Pfannenstiel incision under spinal anesthesia with American Society of Anesthesiologists Classification (ASA) II,fullterm singular pregnancy after receiving the approval of the ethics committee of Ataturk University Medical Faculty Hospital and written approval of the patients
Interventions
Group M will be given a 0.5% Bupivacain Dosage Regimen with weight and height adjustment+15 μg fentanyl +150 μg morphine intrathecally.
DRUGBupivacain
Group LWI+IPLA will given 30 ml %0,5 bupivacaine+%2 lidocaine infiltration and instillation
Sponsors
Ataturk University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Pregnant women * 18-50 age * ASA II * Fullterm singular pregnancy
Exclusion criteria
* Neuraxial anesthesia is contraindicated, * Allergy to the drugs to be used in the study, * Refused to participate in the study, * BMI\>35 kg/m2 * ASA≥3 * Diabetes * Preeclampsia, * Cardiovascular disease * Chronic pain and neuropathic pain, * Given opioids in the operation due to intraoperative pain, * Switched to general anesthesia, * Excessive bleeding during the operation, * Uterine atony * Drain placed in the area to be infiltrated, * History of drug addiction and psychiatric illness, * Understand Visual analog pain scale
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The primary outcome is to compare the total amount of opioids consumed in the first 24 hours postoperatively. | postoperative 24 hours | The primary outcome is to compare the total amount of opioids consumed in the first 24 hours postoperatively. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual Analog Scale (VAS) (0-10) at 2,4,6,12 and 24 hours postoperatively | 2,4,6,12,and 24 hours postoperatively | The VAS is a validated.Possible scores range from 0 (no pain) to 10 (worst possible pain) |
Countries
Turkey (Türkiye)
Outcome results
None listed