Caffine and Endurance Performance
Conditions
Brief summary
Caffeine is a widely used efficacious supplement by both the general public, and athletes, with the goal of improving performance. The effects of caffeine alone are well known, but it is not clear whether a multi-ingredient supplement (containing both caffeine and polyphenols) can affect exercise performance. This study aims to determine if a low dose of caffeine, in the form of a whole-fruit coffee extract also containing polyphenols, can improve exercise performance compared to a placebo condition, with a secondary objective of identifying if this supplement can improve post exercise refuelling (glycogen resynthesis). Participants will consume either the supplement or a placebo before engaging in an exercise protocol. Muscle biopsies will then be obtained so as to measure subsequent glycogen resynthesis, with multiple blood samples being taken through the day. The following morning another biopsy will be taken before the exercise protocol will be repeated. This research will inform us of the efficacy of caffeine and polyphenols on improving exercise performance.
Interventions
DIETARY_SUPPLEMENTCoffeeBerry Supplement
A Coffeeberry supplement containing 200mg Caffeine and 14mg polyphenols, manufactured by FutureCeuticals Inc.,
DIETARY_SUPPLEMENTPlacebo
Placebo
Sponsors
VDF FutureCeuticals Inc.
University of Exeter
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Exclusion criteria
* Allergy to Lidocaine * Exclusion critera * Any diagnosed metabolic health condition * Pregnant * Non-habitual caffeine intake * Smoker * No endurance training * Diagnosed Cardiovascular disease * Beta-Blockers * Recent history of musculoskeletal injury Inclusion criteria: * Age 18-40 * Heathy * Highly trained endurance athletes (V̇O2max: males \>55 and females \>50 mL⋅kg bm-1⋅min-1) * Both males and females are allowed to participate. If females are on the oral contraceptive pill they are to be tested on consecutive weeks. If they are not on the oral contraceptive pill, then female subjects are to be tested every 4 weeks, at the same point of their menstrual cycle.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Exercise performance | 15 Minitues | Amount of work completed in 15 minutes |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Alertness | 1 Minitue | 10 cm visual analog scale (Ranging from Not Alert to Extremly Alert) |
| Motivation | 1 Minitue | 10 cm visual analog scale (Ranging from Not motivated to Extremly motivated) |
| Glycogen Resynthesis | 24 Hours | The diffrence in glycogen within the muscle between two time points |
| Urine osmolarity | 24 Hours | The hydration status of the individual measured in mOsmo\|/kg |
| GI comfort | 1 Minitue | 10 cm visual analog scale (Ranging from No discomfort to Extreme discomfort) |
| Rate of perceived exertion | 1 Minitue | Validated Borg scale (6-20 Arbitrary units) |
Countries
United Kingdom
Outcome results
None listed