Oral Lichen Planus
Conditions
Brief summary
On the basis of previous studies, a validation cohort will be established to explore the relationship between oral lichen planus and autoimmune thyroid diseases, and a disease efficacy prediction strategy can be formed.
Detailed description
For oral lichen planus patients, the prevalence of Hashimoto's thyroiditis will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined. Besides, for patients with Hashimoto's thyroiditis, the prevalence of oral lichen planus will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.
Interventions
OTHERno intervention
Sponsors
The Dental Hospital of Zhejiang University School of Medicine
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* OLP patients without systemic disease
Exclusion criteria
* OLP patients with severe periodontal disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oral lichen planus (OLP) lesions record | 1 year | Record changes of lesions based on the symptoms and signs of the oral lichen planus patient. |
| Level of thyroid function and antibody | 1 year | The levels of thyroid hormone and thyroid autoantibodies in serum of OLP patients were detected. |
Countries
China
Outcome results
None listed