Rosacea
Conditions
Brief summary
Rosacea is a chronic and relapsing inflammatory cutaneous disorder with highly variable prevalence worldwide.
Detailed description
In our study, we will compare the safety, efficacy, and adverse effects of low-dose oral doxycycline alone versus combined with pulsed dye laser or topical brimonidine in treating erythematotelangiectatic rosacea in an attempt to build a treatment strategy in a disease with complex pathogenesis.
Interventions
OTHERtreatment
types
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Patient with current erythematotelangiectatic rosacea
Exclusion criteria
\- Pregnant females. 2-Patients on systemic steroids. 3-Patients complaining of other dermatological disorders mainly photosensitive cutaneous disorder. 4- Patients receiving any systemic treatment including retinoids for the previous 1 month or any topical treatment for the previous 2 weeks or any laser sessions for the previous 3months for erythematotelangiectatic rosacea at least.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical erythema assessment scale | 3 months | clinical scale |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Thickness of capillaries by dermoscope | 3 months | Assessment |
Outcome results
None listed