Diet in the Management of Acromegaly

Impact of Low Carbohydrate and Low Gluten Diet on Acromegaly Progression, Symptoms, Complications, and Treatment Outcomes

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05401084

Enrollment

Registered

2022-06-02

Start date

2024-09-20

Completion date

2025-03-01

Last updated

2024-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acromegaly

Brief summary

Impact of low carbohydrate and low gluten diet on acromegaly progression, symptoms, complications, and treatment outcomes.

Interventions

OTHERDiet

Macronutrient diet changes.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Diagnosis of acromegaly.

Exclusion criteria

* Diet restrictions.

Design outcomes

Primary

Measure	Time frame	Description
Change in insulin-like growth factor 1 (IGF-1).	8 weeks	Change in IGF-1 will be assessed from baseline (pre-intervention) to end of follow up.
Change in growth hormone level (GH).	8 weeks	Change in GH level will be assessed from baseline (pre-intervention) to end of follow up.
Change in acromegaly related symptoms.	8 weeks	Change in acromegaly related symptoms will be assessed from baseline (pre-intervention) to end of follow up using Acromegaly Quality of Life Questionnaire (AcroQoL).

Countries

United States

Contacts

Primary ContactVivian Hwe

Vivian.Hwe@cshs.org424-315-4489

Backup ContactDaniel Gomez

424-315-4489

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026