Chemical Profiling of Colorectal and Pancreatic Cancers Using Breath Analysis - Feasibility Study

Detection of Colorectal and Pancreatic Cancers Using Breath Analysis - Feasibility Study.

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05400408

Acronym

Cancer

Enrollment

250

Registered

2022-06-01

Start date

2024-05-01

Completion date

2025-03-31

Last updated

2024-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer, Pancreatic Cancer

Brief summary

Detection of Colorectal and Pancreatic Cancers Using Breath Analysis - Feasibility Study

Detailed description

A diagnostic prospective study with no anticipated risks or constraints. Main Objective: To quantify differences in exhaled breath VOCs of patients with colorectal or pancreatic cancers compared with cohorts without cancer.

Interventions

DIAGNOSTIC_TESTVOX

Breath Biopsy Analysis

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Intervention model description

Parallel Assignment

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Yes

Inclusion criteria

* Age 18 to 85 years at the time of consent. * Scheduled for colonoscopy or Endoscopic Retrograde Cholangio Pancreatography. * Fasted \>6 hours, consuming water only. * Able to provide informed written consent.

Exclusion criteria

* Lacks capacity or is unable to provide informed written consent. * Pregnant or lactating woman. * Histologically confirmed cancer in any organ.

Design outcomes

Primary

Measure	Time frame	Description
identification of Volatile Organic Compounds that can be related to Colorectal malignancy.	Through the study completion, up to 1 year.	Comparison of identity and concentration of Volatile Organic Compounds profile found among colorectal patients and the identity and concentration of Volatile Organic Compounds profile found among Healthy controls.

Secondary

Measure	Time frame	Description
Test Sensitivity and specificity for colorectal polyps.	Through the study completion, up to 1 year.	Comparison of Volatile Organic Compounds found among subjects with and without colorectal polyps.
Test Sensitivity and specificity for pancreatic cancer.	Through the study completion, up to 1 year.	Comparison of Volatile Organic Compounds found among pancreatic patients and Healthy controls.

Countries

Israel

Contacts

Primary ContactHAREL HERSHTIK

harel.hershtik@gmail.com0546641812

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026