Atrophic Maxilla
Conditions
Brief summary
Assessment of bone quality and quantity for three dimensional bone augmentation for maxilla using titanium meshes loaded with bone marrow aspirate mixed with xenograft versus xenograft mixed with autografts only
Interventions
PROCEDUREThree dimensional maxillary bone augmentation
mixing of bone marrow aspirate concentrate with xenograft to show the bone quality and bone gain compared to the xenografts mixed with autografts
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients are free from any systemic conditions and bone metabolic diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing. * Edentulous anterior or posterior maxilla with deficient alveolar ridge that is less than 5 mm measured from the crest of the alveolar ridge to the nasal or maxillary sinus and less than 4mm in buccolingual width. * The minimum number of missing teeth in the alveolar ridge is two adjacent teeth.
Exclusion criteria
* Intra-bony lesions (e.g. cysts) or infections (e.g. abscess) that may retard the osteotomy healing. * Previous grafting procedures in the edentulous area.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Histomorphometric bone analysis | 4 months | ratio of mineralized tissue to non mineralized tissue |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Alveolar ridge vertical bone and horizontal bone gain | 4 months | Gain measured in millimeters on a cone beam computed tomograpghy |
Countries
Egypt
Outcome results
None listed