PONV
Conditions
Keywords
transcutaneous electrical acupoint stimulation, liver surgery
Brief summary
Incidence of postoperative nausea and vomiting (PONV) could be high as 60% after liver surgery. Acupoint stimulation has been proved to decrease PONV. In this study, we will investigate the effect of transcutaneous electrical acupoint stimulation on incidence of PONV after liver surgery.
Interventions
DEVICEtranscutaneous electrical acupoint stimulation
Electrodes are placed at acupoints and connected to the stimulator. Electrical stimulation is given during surgery.
Sponsors
Zhihong LU
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
The stimulator is put in an opaque box
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age ≥18 years * scheduled for elective liver surgery under general anesthesia
Exclusion criteria
* body mass index less than 18 kg/m2 or higher than 30 kg/m2 * American Society of Anesthesiologists status higher than Ⅲ * patients with contraindication to transcutaneous electrical stimulation, including skin damage, infection or implantable electrical device * suspected or existed abuse of drug or alcohol * pregnant or breeding women * history of neurological or psychiatric disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of nausea and vomiting by 24 hours after surgery | from end of surgery to 24 hours after surgery, in a total of 24 hours |
Secondary
| Measure | Time frame |
|---|---|
| incidence of nausea and vomiting in PACU (post-anesthesia care unit) | from end of surgery to discharge from PACU(post-anesthesia care unit), in an average of 30 minutes |
| score of nausea and vomiting by 24 hours after surgery | from end of surgery to 24 hours after surgery, in a total of 24 hours |
| score of nausea and vomiting by 48 hours after surgery | from end of surgery to 48 hours after surgery, in a total of 48 hours |
| score of nausea and vomiting in PACU(post-anesthesia care unit) | from end of surgery to discharge from PACU, in an average of 30 minutes |
| incidence of nausea and vomiting by 48 hours after surgery | from end of surgery to 48 hours after surgery, in a total of 48 hours |
| Quality of recovery score at 48 hours after surgery | from end of surgery to 48 hours after surgery, in a total of 48 hours |
| postoperative in-hospital stay | from end of surgery to discharge from hospital, in an average of 7 days |
| death by 6 months after surgery | from end of surgery to 6 months after surgery, in a total of 6 months |
| Quality of recovery score at 24 hours after surgery | from end of surgery to 24 hours after surgery, in a total of 24 hours |
Contacts
Primary ContactZhihong Lu
Backup ContactShan He
Outcome results
None listed