ICU Acquired Weakness
Conditions
Keywords
ICU acquired weakness, Muscle strength, fatigability, respiratory muscle, Quadriceps muscle
Brief summary
Muscle dysfunction can be lead to poor outcomes moreover ICU muscle weakness recovery are not correctly described. The investigators aimed to assess the ability for quadriceps or respiratory muscles to repeat an effort at a maximal loading.
Interventions
DIAGNOSTIC_TESTMuscle evaluation
Repeated maximal voluntary contraction
Sponsors
Groupe Hospitalier du Havre
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Mechanically ventilated at least at 24 Hours * Maximal inspiratory pressure \< 30 centimeter of water * MRC score \< 48/60
Exclusion criteria
* Age \< 18 years * Patients with neurological pathology or pre existing neuromuscular dysfunction * Patient unable to walk 50 meters before ICU admission * Patient with a thoracic or abdominal surgery * Inability to carry out maximal voluntary contraction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Respiratory muscle strength | One day | Respiratory muscle strength will be assessed by Maximal Inspiratory pressure in centimeter of water. The measure will carry out by an electronical manometer |
| Change in quadriceps muscle strength | One day | Quadriceps muscle strength will be assessed by Maximal Voluntary contraction of the quadriceps in Newton. The measure will carry out by an electronical dynamometer |
Countries
France
Outcome results
None listed