Chronic Kidney Diseases
Conditions
Keywords
chronic kidney disease, kidney transplantation, comprehensive geriatric assessment
Brief summary
Geriatric assessment is now widely used to decide whether older patients with chronic kidney disease should be put on the kidney transplantation waiting list. This study aims to evaluate the association between Geriatric assessment and inscription on kidney transplantation.
Detailed description
There is a high proportion of older patients among patients with kidney failure, raising the question of the access to kidney transplantation within these patients. Geriatric assessment is now widely used to decide whether older patients with chronic kidney disease should be put on the kidney transplantation waiting list. This study aims to evaluate the association between Geriatric assessment and inscription on kidney transplantation. Secondary objectives includes the analysis of the association between Geriatric assessment and: * post-kidney transplantation outcomes * quality of life. It also includes the evolution of Geriatric assessment while still on waiting list and after kidney transplantation. This study takes place in an University Hospital in Caen, France. This hospital is the only one performing kidney transplantation in the three French departments around. Candidates for kidney transplantation older than 70 years are systematically evaluated by a trained nurse and a geriatrician to perform a comprehensive geriatric assessment, evaluating cognitive functions, risk of fall, nutrition, frailty, functional status, and depressive symptoms. These patients are followed-up each year while still on the waiting list, and once after kidney transplantation. All patients evaluated within this consultation are proposed to enter the study. Patients are excluded in case of refusal or if they are unable to provide informed consent. The inclusion began in January 2019.
Interventions
OTHERGeriatric assessment
Geriatric assessment by a trained nurse and a geriatrician for older kidney transplantation candidates in Caen University Hospital. The geriatric assessment includes a evaluation of cognitive functions, depressive symptoms, risk of fall, nutrition, frailty, and functional status.
Sponsors
University Hospital, Caen
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Inclusion criteria
* All patients addressed for Geriatric assessment before inscription on kidney transplantation waiting list in Caen University Hospital, France
Exclusion criteria
* Patient refusal * Patient unable to provide informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Inscription on kidney transplantation waiting list | 6 months | Inscription on kidney transplantation waiting list |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Length of hospitalization in the year following kidney transplantation | 1 year after kidney transplantation | Units: days |
| Delayed renal recovery following kidney transplantation | 1 week after kidney transplantation | Dialysis requirement during the first week after kidney transplantation |
| Mortality | 1 year after kidney transplantation | Death in the year following kidney transplantation |
Other
| Measure | Time frame | Description |
|---|---|---|
| Evolution of frailty while on waiting list and after kidney transplantation | 1 year after kidney transplantation | Frailty assessed by the Rockwood scale |
| Evolution of quality of life while on waiting list and after kidney transplantation | 1 year after kidney transplantation | Assessed by the SF12 score before and in the year after kidney transplantation |
| Evolution of functionnal status while on waiting list and after kidney transplantation | 1 year after kidney transplantation | Functionnal status assessed by activities of daily living scales |
| Evolution of cognitive functions while on waiting list and after kidney transplantation | 1 year after kidney transplantation | Cognitive functions assessed by MMSE score |
| Evolution of executive functions while on waiting list and after kidney transplantation | 1 year after kidney transplantation | Executive functions assessed by BREF test |
| Evolution of mood while on waiting list and after kidney transplantation | 1 year after kidney transplantation | Mood assessed by the mini GDS scale |
Countries
France
Contacts
Primary ContactCédric Villain, MD, PhD
Outcome results
None listed