Dosimetric Comparison of Three Radiation Techniques for Hypofractionated Whole Breast Radiotherapy in Early Breast Cancer

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05394194

Enrollment

Registered

2022-05-27

Start date

2022-07-20

Completion date

2025-08-01

Last updated

2022-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Keywords

computer assisted, radiotherapy

Brief summary

We aim to compare three different radiation delivery techniques, namely three-dimensional conformal radiation therapy (3D-CRT), intensity modulated radiotherapy (IMRT) and volumetric modulated radiation therapy (VMAT) in left-sided early breast cancer patients.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* left sided early breast cancer patients. Should have histopathological prove to have invasive breast cancer. Operated by breast conservative surgery. Have no associated comorbidities

Exclusion criteria

* locally advanced breast cancer. Patients who have total mastectomy. Patients who had previous chest irradiation or known comorbidities.

Design outcomes

Primary

Measure	Time frame	Description
Comparison of coverage of planned target volume(PTV) among the three plans.	1 year	PTV coverage in dose is compared among the three plans.
Comparison of doses to organs at risk among the three plans.	1 year	mean dose of the heart, lung volume receiving 20Gy, esophageal doses will be compared among the three plans

Secondary

Measure	Time frame
Comparison of target homogeneity among the three plans.	1 year

Contacts

Primary ContactAlshaymaa Abdelghaffar, PhD

alshimaaahmed@med.sohag.edu.eg01006828975

Backup ContactEmad Eldin Nabil Hassan, PhD

emadd122@yahoo.com01227014556

Outcome results