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The Effects of Weight Loss on Psoriatic Arthritis

The Effect of Body Weight Management and Cognitive Exercise Therapy Approach on Psoriatic Arthritis Symptoms

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05393141
Enrollment
48
Registered
2022-05-26
Start date
2022-01-30
Completion date
2022-10-15
Last updated
2022-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Psoriatic Arthritis

Keywords

psoriatic arthritis, diet, biopsychosocial exercise

Brief summary

Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. This study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach (BETY-Bilişsel Egzersiz Terapi Yöntemi) interventions on symptoms. Accordingly, 45 overweight/obese subjects with PSA aged 20-65 years will divide into diet, diet+bety, and control groups. Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at the end of the study.

Detailed description

Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. The present study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach interventions on symptoms. * Fourt-five overweight/obese subjects with PSA aged 20-65 years will divide into diet (n=15), diet+bety (n=15), and control (n=15) groups. * Individually diet programs will be applied according to the metabolic, biochemical, and physical activity status of the subjects prepared by a registered dietitian. * BETY exercise training will be given by a registered physiotherapist. * The subjects will be followed for 12 weeks. * Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at study completion.

Interventions

BEHAVIORALdiet and biopsychosocial exercise intervention

dietary intervention: biopsychosocial exercise intervention:

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* overweight/obese * diagnosed with PSA

Exclusion criteria

* pregnancy or lactation

Design outcomes

Primary

MeasureTime frameDescription
Weight LossAt the end of 3 monthsBMI (kilogram/metre2(kg/m2))
DAPSA scoreAt the end of 3 monthsThe score ranges from 0 to 50 points, with increased score reflect more discomfort

Secondary

MeasureTime frameDescription
Quality of Life ScoreAt the end of 3 monthsThe score ranges from 0 to 100 points, with increased score reflecting improved quality of life

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026