Interstitial Lung Disease, Rheumatoid Arthritis
Conditions
Keywords
rheumatoid arthritis, Interstitial Lung Disease
Brief summary
The quantitative and qualitative analysis of RA lung involvement in the Hungarian population
Detailed description
Interstitial lung disease (ILD) accounts for a significant proportion of mortality and morbidity in rheumatoid arthritis (RA). The aim of this prospective longitudinal study is to asess the interstitial lung involvement in Hungarian rheumatoid arthritis patients. Laboratory markers, X-ray based imaging methods, pulmonological functional tests, QOL questionnaire and sleep quality assessement questionnaire are used to estimate the interstitial lung disease. Also smaller cross-sectional studies about the imaging parameters and a national register is planned to be created based on these data.
Interventions
None listed
Sponsors
Medical Imaging Centre- Semmelweis University, Faculty of Medicine
Department of Pulmonology, Semmelweis University Faculty of Medicine
Polyclinic of the Hospitaller Brothers of St. John of God, Budapest
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* diagnosis of RA
Exclusion criteria
* pregnancy, breastfeeding * previous diagnosis of ILD, lung cancer, registered lung infection in the last 2 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pattern of ILD | From baseline to at least 5 years | to characterize the ILD patterns based on imaging methods |
| Prevalence of ILD | From baseline to at least 5 years | detection of ILD with imaging methods |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation with biomarkers | From baseline to at least 2 years | correlation of the imaging results with respiratory function, disease activity and laboratory markers |
Countries
Hungary
Contacts
Primary ContactKinga Fritsch, MD
Backup ContactJudit Majnik, MD PhD
Outcome results
None listed