Identification of Risk Factors for Cardiovascular Disease and Cancer in Korean Population: A Prospective Cohort Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05389956

Enrollment

510000

Registered

2022-05-25

Start date

2023-01-01

Completion date

2052-08-31

Last updated

2024-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases, Malignancy, Risk Factor

Keywords

Cardiovascular disease, Malignancy, Risk factor

Brief summary

Cancer and cardiovascular disease are the global leading causes of death. These two disease entities are multifactorial disease that are caused by several factors. The aim of this prospective cohort study was to investigate the status of risk factors profiles and health related behavior in Korean population, and to discover novel risk factors associated with the occurrence of endpoint events.

Detailed description

This is a single center, observational, prospective cohort study. The primary outcomes include the incidence of MACE (major adverse cardiovascular events) and the incidence of any malignancy. We plan to collect the baseline information at enrollment and the occurrence of clinical endpoint events will be followed for at least 10 years. The study will enroll 510,000 subjects aged ≥19 years who underwent a general health screening in Korea.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Men or women aged 19 years and older who underwent a general health screening at the health promotion center of Ulsan University Hospital (Ulsan, Korea) * Subjects have to agree to participate by signing a consent

Exclusion criteria

* Subjects who cannot or reject to sign the consent form.

Design outcomes

Primary

Measure	Time frame	Description
Major adverse cardiovascular event (MACE)	10 year	A major adverse cardiovascular event (MACE) of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke
Incidence of malignancy	10 year	The occurrence of any malignancy of interest

Secondary

Measure	Time frame
Myocardial infarction	10 year
All-cause death	10 year
Cancer related mortality	10 year
Stroke	10 year
Cardiovascular death	10 year

Countries

South Korea

Contacts

Primary ContactSangwoo Park, MD

warya7@naver.com82-52-250-8669

Outcome results