Health Consequences of the Burden of Atrial Fibrillation

Health Consequences of the Burden of Atrial Fibrillation - The Swiss-AF-BURDEN Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05389228

Acronym

SwissAF-BURDEN

Enrollment

325

Registered

2022-05-25

Start date

2018-08-01

Completion date

2024-01-07

Last updated

2024-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation, Burden

Keywords

Atrial Fibrillation, Burden

Brief summary

The Swiss-AF-BURDEN study will be embedded in the follow-up visits of the Swiss-AF cohort study. The research question of the current atrial fibrillation burden will be answered by using 7-day Holter-ECG recordings and continuous implanted loop recorder recording, whereas cardiac MRI examination will give results about cardiac dimensions and function. The 7-day Holter ECG will be repeated after one year. The cMRI will be performed separately or directly after the brain MRI to minimize the additional burden for the patients. Only a subsample of 100 patients will additionally receive ILR for 2 years.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

45 Years to No maximum

Healthy volunteers

Inclusion criteria

* Swiss-AF study patient * Paroxysmal or persistent AF

Exclusion criteria

* Permanent AF * Swiss-AF patients not willing or able to undergo 7-day Holter monitoring * Specifically for cMRI: Pregnant women or women of child-bearing age without a prior negative pregnancy test

Design outcomes

Primary

Measure	Time frame	Description
AF-burden	Baseline to Follow-up year 2	The burden of AF is defined as the amount of time (percentage) in AF during rhythm monitoring

Secondary

Measure	Time frame	Description
Incidence of overt and covert stroke	Baseline to Follow-up year 2	Number of participants with overt and covert stroke

Countries

Switzerland

Outcome results